The Indianapolis Colts find themselves in need to lean on backup quarterback Jacob Brissett to start the 2019 NFL Season, after Andrew Luck announced his retirement at a press conference on Sunday, August 25th, 2019

Andrew has been sitting-out during the entire preseason while recovering from an ankle injury and was listed as “doubtful” for NFL Week 1.

Online betting sites were obligated to quickly adjust their odds, dropping the Colts from -140 favorites to +600 underdogs. Also, sportsbooks moved them from being 18 to 1 favorites to 40 to 1.